Euphorbia hirta has been widely used by Tribal as traditional medicine in a treatment against infectious pathogens. E. hirtaLinn. is a perennial. diffusion method was used to determine the antibacterial activity on gram negative: Euphorbia hirta plant displayed an excellent antibacterial activity against K. The antibacterial and antifungal effect of Euphorbia hirta was evaluated against a panel of bacteria (Escherichia coli, Psueudomonas aeruginosa, Klebsiella.

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Out of fungi; A. There is a continuous and urgent need to discover new antimicrobial compounds with diverse chemical structures and novel mechanisms of action for new and reemerging infectious diseases.

Screening of the plant under investigation E. J Med Plant Res. Two flavonoids quercetin and kaempferol were identified in the bound flavonoids of stem extract which showed activity against all the microorganisms. Footnotes Source of Support: In the current investigation E.

Screening for antimicrobial activity Disc diffusion assay was performed for antimicrobial screening. National Center for Biotechnology InformationU. TA and quantity of extracts from plant parts was calculated and recorded [ Table 6 ]. TA is the volume at which the test extract can be diluted with the ability to kill the microorganisms. In Nigeria, extracts or exudates of the plant are used as ear drops and in the treatment of boils, sore, and promoting wound healing.


Antimicrobial activity of selected Peruvian medicinal plants. Table 2 Antibacterial activity of flavonoids of Euphorbia hirta by disc diffusion assay. Bonjar G, Farrokhi PR. In the present investigation lowest MIC value 0. Please review our privacy policy. Ethyl ether free flavonoid and ethyl acetate fractions bound flavonoids thus obtained were dried in vaccuo and weighed.

Present investigation proves the plant under study to possess broad spectrum antimicrobial activity. Table 6 Quantity and total activity of free and bound flavonoids of Euphorbia hirta. Elutes were pooled, completely dried, and rechromatographed to test the purity of the isolated compound. Assessment of bioactivity of Indian medicinal plants using Brine Shrimp Artemia salina lethality assay.

TA indicates the volume at which extracts can be diluted without losing the ability to kill microorganisms. Antibiotic resistance has become a global concern.

Phytochemical study and screening for antimicrobial activity of flavonoids of Euphorbia hirta

Subramanian SS, Nagarjan S. MIC was determined for the plant extract showing antimicrobial activity against test pathogens. Petroleum ether fractions were discarded as being rich in fatty substances, whereas ethyl ether and ethyl acetate fractions were analyzed for free and bound flavonoids, respectively.

Niger J Nat Prod Med. Full TA calculated against E. Total activity TA of extracts against each sensitive pathogen was also evaluated.

Free and bound flavonoid extract exhibited good inhibitory activity against most of the pathogens. The turbidity of the wells in the microtiter plate was interpreted as visible growth of microorganisms. The study was carried out along with standard drugs terbinafine and itraconazol for fungus and streptomycin for bacteria. Free antimcirobial bound flavonoids from root, stem leaf, and fruits of E.


Euphorbia hirta belonging to family Euphorbiaceae is a medicinal, rhizomatous herb distributed in southern Western Ghats of India and northern east coast of Tamil Nadu. Plant parts were separately fuphorbia dried and finely powdered using a mixer. In the present study, total eight extracts of different parts of plants were tested for their bioactivity.

Antibacterial activity of traditional Australian medicinal plants.

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These plates were developed in an organic solvent mixture of benzene, acetic acid, and water TA determination TA is the volume at which the test extract can be diluted with the ability to kill the microorganisms. This study aims to phytochemical and antimicrobial study of Euphorbia hirta Euphorbiaceae. Flavonoids of the seeds of Crotolaria retusa and Ctotolaria striata.

Author information Activjty notes Copyright and License information Disclaimer. Euphorgia sample specimen with No. Euphorbia hirtaflavonoid, kaempferol, minimum inhibitory concentration, quercetin, total activity. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.